Publications – Pancreas

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2026, European Journal of Pharmaceutical Sciences, M4 drug discovery: Human drug predictions from integrated preclinical insights exemplified with a GLP-1R agonist
Silfvergren O, Rigal S, Schimek K, Simonsson C, Kanebratt KP, Forschler F, Yesildag B, Marx U, Vilén L, Gennemark P, Cedersund G

2024, Communications Biology, Vol. 7, Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system
Rigal S, Casas B, Kanebratt KP, Wennberg Huldt C, Magnusson LU, Mullers E, Karlsson F, Clausen M, Hansson SF, Jansson Lofmark R, Ammala C, Marx U, Gennemark P, Cedersund G, Andersson TB, Vilen LK

2024, Stem Cell Reports, Vol. 19, Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility
Pamies D, Ekert J, Zurich MG, Frey O, Werner S, Piergiovanni M, Freedman BS, Teo AKK, Erfurth H, Reyes DR, Loskill P, Candarlioglu P, Suter-Dick L, Wang S, Hartung T, Coecke S, Stacey GN, Atac Wagegg B, Dehne EM, Pistollato F, Leist M

2017, Nature Scientific Reports, Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model
Bauer S, Wennberg Huldt C, Kanebratt KP, Durieux I, Gunne D, Andersson S, Ewart L, Haynes WG, Maschmeyer I, Winter A, Ämmälä C, Marx U, Andersson TB