The HUMIMIC Chip 4 enables easy integration of up to four different organ models, e. g. a combination of intestine, liver, kidney and neuronal tissue in one system.

Product description

The PBPK-compliant design allows for quantitative in vitro to in vivo extrapolation. The HUMIMIC Chip 4 uses two separate microfluidic circuits to model processes like excretion and reabsorption of various substances in the kidney model.



  • Efficient, lifelike tissue nutrition of up to four organ models
  • Supports relevant PK/PD modeling for quantitative in vitro to in vivo extrapolation and determination of ADME profiles (absorption, distribution, metabolism and excretion)
  • Long-term repeated performance
  • Physiological shear stress applicable
  • Enables multi-organ disease modelling
HUMIMIC Chip4Zusatz