The HUMIMIC Chip 4 enables easy integration of up to four different organ models, e. g. a combination of intestine, liver, kidney and neuronal tissue in one system.

Product description

The PBPK-compliant design allows for quantitative in vitro to in vivo extrapolation. The HUMIMIC Chip4 uses two separated microfluidic circuits to model processes like excretion and reabsorption of various substances in the kidney model.



  • Efficient, lifelike tissue nutrition of up to four organ models
  • Supports relevant PK/PD modeling for quantitative in vitro to in vivo extrapolation and determination of ADME profiles (absorption, distribution, metabolism and excretion)
  • Long-term repeated performance
  • Physiological shear stress applicable
  • Enables multi-organ disease modelling
HUMIMIC Chip4Zusatz