Publications

2017, BIOspektrum, Miniaturisierte menschliche Organe auf dem Chip
Hasenberg T, Dehne EM, Lauster R, Marx U

2017, Future Science, The ascendance of microphysiological systems to solve the drug testing dilemma
Dehne EM, Hasenberg T, Marx U

2017, Front. Bioeng. Biotechnol., Engineering Blood and Lymphatic Microvascular Networks in Fibrin Matrices
Knezevic L, Schaupper MV, Muehleder S, Schimek K, Hasenberg T, Marx U, Priglinger E, Redl HR, Holnthoner W

2016, Advances in Experimental Medicine and Biology, Validation of Bioreactor and Human-on-a-Chip Devices for Chemical Safety Assessment
Rebelo SP, Dehne EM, Brito C, Horland R, Alves PM, Marx U

2016, ALTEX, Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing
Marx U, Andersson TB, Bahinski A, Beilmann M, Beken S, Cassee FR, Cirit M, Daneshian M, Fitzpatrick S, Frey O, Gaertner C, Giese C, Griffith L, Hartung T, Heringa MB, Hoeng J, de Jong WH, Kojima H, Kuehnl J, Leist M, Luch A, Maschmeyer I, Sakharov D, Sips AJ, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tralau T, Tsyb S, van de Stolpe A, Vandebriel R, Vulto P, Wang J, Wiest J, Rodenburg M, Roth A

2015, Vitro Toxicology, The promise and potential of "Organs-on-Chips" as preclinical models; Applied In Vitro Toxicology
A Bahinski, R Horland, D Huh, C Mummery, DA Tagle, T MacGill

2015, Journal of Biotechnology, Emulating human microcapillaries in a multi-organ-chip platform
T Hasenberg, S Mühleder, A Dotzler, S Bauer, K Labuda, W Holnthoner, H Redl, R Lauster, U Marx

2015, ALTEX, Workshop Report: Non-Animal Models of Epithelial Barriers (Skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology
S Gordon, M Daneshian, J Bouwstra, F Caloni, S Constant, DE Davies, G Dandekar, CA Guzman, E Fabian, E Haltner, T Hartung, N Hasiwa, P Hayden, H Kandarova, S Khare, HF Krug, C Kneuer, M Leist, G Lian, U Marx, M Metzger, K Ott, P Prieto, MS Roberts, EL Roggen, T Tralau, C van den Braak, H Walles

2015, Lab on a Chip, A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
I Maschmeyer, AK Lorenz, K Schimek, T Hasenberg, AP Ramme, J Hübner, M Lindner, C Drewell, S Bauer, A Thomas, NS Sambo, F Sonntag, R Lauster, U Marx

2015, European Journal of Pharmaceutics and Biopharmaceutics, Chip-based human liver–intestine and liver–skin co-cultures – A first step toward systemic repeated dose substance testing in vitro
I Maschmeyer, T Hasenberg, A Jaenicke, M Lindner, AK Lorenz, J Zech, LA Garbe, F Sonntag, P Hayden, S Ayehunie, R Lauster, U Marx, EM Materne

2015, Journal of Visualized Experiments, The Multi-organ Chip - A Microfluidic Platform for Long-term Multi-tissue Coculture
EM Materne, I Maschmeyer, AK Lorenz, R Horland, K Schimek, M Busek, F Sonntag, R Lauster, U Marx

2015, Journal of Biotechnology, A multi-organ chip co-culture of neurospheres and liver equivalents for long-term substance testing
EM Materne, AP Ramme, A Terrasso, M Serra, P Alves, C Brito, D Sakharov, A Tonevitsky, R Lauster, U Marx

2014, Advanced Drug Delivery Reviews, Human immunity in vitro - Solving immunogenicity and more
C Giese, U Marx

2013, Lab on a Chip, Integrating biological vasculature into a multi-organ-chip microsystem
K Schimek, M Busek, S Brincker, B Groth, S Hoffmann, R Lauster, G Lindner, AK Lorenz, U Menzel, F Sonntag, H Walles, U Marx, R Horland

2013, Lab on a Chip, Chip-based liver equivalents for toxicity testing - organotypicalness versus cost-efficient high throughput
EM Materne, A Tonevitsky, U Marx

2013, Lab on a Chip, A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture
I Wagner, EM Materne, S Brincker, U Süßbier, C Frädrich, M Busek, F Sonntag, D Sakharov, E Trushkin, A Tonevitsky, R Lauster, U Marx

2013, Lab on a Chip, Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion
B Ataҫ, I Wagner, R Horland, R Lauster, U Marx, A Tonevitsky, A Azar, G Lindner

2013, Analyst, Fluorescent optical fiber sensors for cell viability monitoring
I Sergachev, A Rusanov, E Trushkin, D Sakharov, U Marx, A Tonevitsky

2012, Alternatives to Lab Animals, 'Human-on-a-chip' developments: a translational cutting-edge alternative to systemic safety assessment and efficiency evaluation of substances in laboratory animals and man?
U Marx, H Walles, S Hoffmann, G Lindner, R Horland, F Sonntag, U Klotzbach, D Sakharov, A Tonevitsky, R Lauster

2012, Biotechnology Journal, Monitoring and control of microbioreactors: an expert opinion on development needs
KV Gernaey, F Baganz, E Franco-Lara, F Kensy, U Krühne, M Luebberstedt, U Marx, E Palmqvist, A Schmid, F Schubert, CF Mandenius

2012, The International Journal of Artificial Organs, Crosstalk between immune cells and mesenchymal stromal cells in a 3D bioreactor system
M Seifert, A Lubitz, J Trommer, D Könnig, G Korus, U Marx, HD Volk, G Duda, G Kasper, K Lehmann, M Stolk, C Giese

2012, Landes Bioscience and Springer Science + Business Media, "Trends in Cell Culture Technology." In Balls M, Combes R, & Bhogal, N, New Technologies for Toxicity Testing (26-46)
U Marx

2011, BMC Proceedings, Human hair follicle equivalents in vitro for transplantation and chip-based substance testing
R Horland, G Lindner, I Wagner, B Atac, S Hoffmann, M Gruchow, F Sonntag, U Klotzbach, R Lauster, U Marx

2011, Sensors and Actuators, Biological cardio-micro-pumps for micro­bio­reactors and analytical micro-systems
M Pilarek, P Neubauer, U Marx

2011, BIOspektrum, Miniaturisierte humane organtypische Zell- und Gewebekulturen
F Sonntag, M Gruchow, I Wagner, G Lindner, U Marx

2011, Journal of Biotechnology, De novo formation and ultra-structural characterization of a fiber-producing human hair follicle equivalent in vitro
G Lindner, R Horland, I Wagner, B Atac, R Lauster

2011, Experimental Dermatology, Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles
A Ariza de Schellenberger, R Horland, M Rosowski, R Paus, R Lauster, G Lindner

2010, Journal of Biotechnology, Design and prototyping of a chip-besed multi-micro-organoid culture system for substance testing, predictive to human (substance) exposure
F Sonntag, N Schilling, K Mader, M Gruchow, U Klotzbach, G Lindner, R Horland, I Wagner, R Lauster, S Howitz, S Hoffmann, U Marx

2010, Journal of Biotechnology, Immunological substance testing on human lymphatic micro-organoids in vitro
C Giese, A Lubitz, CD Demmler, J Reuschel, K Bergner, U Marx

2010, BIOforum Europe, Organotypic tissue cultures for substance testing
R Pörtner, C Burger, K Maier-Reif, C Goepfert, S Hoffmann, A Scriba, U Marx