Publikationen – Niedermolekulare Substanzen

2023, ALTEX, A microfluidic thyroid-liver platform to assess chemical safety in humans
Kühnlenz J, Karwelat D, Steger-Hartmann T, Raschke M, Bauer S, Vural Ö, Marx U, Tinwell H, Bars R

2021, Drug Testing and Analysis, Early view, Organ-on-a-chip: Determine feasibility of a human liver microphysiological model to assess long-term steroid metabolites in sports drug testing
Görgens C, Ramme AP, Guddat S, Schrader Y, Winter A, Dehne EM, Horland R, Thevis M

2021, Journal of Applied Toxicology, Early view, Demonstration of the first‐pass metabolism in the skin of the hair dye, 4‐amino‐2‐hydroxytoluene, using the Chip2 skin–liver microphysiological model
Tao TP, Brandmair K, Gerlach S, Przibilla J, Géniès C, Jacques‐Jamin C, Schepky A, Marx U, J. Hewitt N, Maschmeyer I, Kühnl J

2021, Toxicology, Vol. 448, Characterization of application scenario-dependent pharmacokinetics and pharmacodynamic properties of permethrin and hyperforin in a dynamic skin and liver multi-organ-chip model
Kühnl J, Tao TP, Brandmair K, Gerlach S, Rings T, Müller-Vieira U, Przibilla J, Genies C, Jaques-Jamin C, Schepky A, Marx U, J. Hewitt N, Maschmeyer I

2020, Scientific reports. Vol. 10, Repeated dose multi-drug testing using a microfluidic chip-based coculture of human liver and kidney proximal tubules equivalents
Lin N, Zhou X, Geng X, Drewell C, Hübner J, Li Z, Zhang Y, Xue M, Marx U, Li B

2020, In Vitro Cellular & Developmental Biology – Animal, The microfollicle: a model of the human hair follicle for in vitro studies
Ataç B, Kiss FM, Lam T, Fauler B, Edler C, Hu P, Tao TP, Jädicke M, Rütschle I, Azar RP, Youngquist S, Mielke T, Marx U, Lauster R, Lindner G, DiColandrea T

2020, International Journal of Pharmaceutics, Vol. 589, Toxicity of topically applied drugs beyond skin irritation: Static skin model vs. Two organs-on-a-chip
Tavares RSN, Tao TP, Maschmeyer I, Maria-Engler SS, Schäfer-Korting M, Winter A, Zoschke C, Lauster R, Marx U, Gaspar LR

2020, Advanced Science, Metal‐Specific Biomaterial Accumulation in Human Peri‐Implant Bone and Bone Marrow
Schoon J, Hesse B, Rakow A, Ort MJ, Lagrange A, Jacobi D, Winter A, Huesker K, Reinke S, Cotte M,Tucoulou R, Marx U, Perka C, Duda GN, Geissler S

2020, Human Reproduction, Vol. 35, A multi-organ-chip co-culture of liver and testis equivalents: a first step toward a systemic male reprotoxicity model
Baert Y, Ruetschle I, Cools W, Oehme A, Lorenz A, Marx U, Goossens E, Maschmeyer I

2020, Scientific Reports, Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies
Schimek K, Frentzel S, Luettich K, Bovard D, Rütschle I, Boden L, Rambo F, Erfurth H, Dehne EM, Winter A, Marx U, Hoeng J