Publikationen – Immuno

2025, bioRxiv, preprint, Integration of lymphatic vasculature to a human lymph node-on-chip enhances physiological immune properties
Morrison AI, Jäger J, de Winde CM, Roest HP, van der Laan LJW, Gibbs S, Koning JJ, Mebius RE

2025, Frontiers in Immunology, Vol. 16, Modeling human natural killer cell development and drug response in a microfluidic bone marrow model
Koenig L, Ben-Eliezer I, Tao TP, Winter A, Grossman M

2024, Cells, Vol. 13, SARS-CoV-2 Spike Protein Amplifies the Immunogenicity of Healthy Renal Epithelium in the Presence of Renal Cell Carcinoma
Somova M, Simm S, Ehrhardt J, Schoon J, Burchardt M, Pinto PC

2024, Stem Cell Reports, Vol. 19, Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility
Pamies D, Ekert J, Zurich MG, Frey O, Werner S, Piergiovanni M, Freedman BS, Teo AKK, Erfurth H, Reyes DR, Loskill P, Candarlioglu P, Suter-Dick L, Wang S, Hartung T, Coecke S, Stacey GN, Atac Wagegg B, Dehne EM, Pistollato F, Leist M

2022, Pharmaceutics, Vol. 14, Proof-of-Concept Organ-on-Chip Study: Topical Cinnamaldehyde Exposure of Reconstructed Human Skin with Integrated Neopapillae Cultured under Dynamic Flow
Vahav I, Thon M, van den Broek LJ, Spiekstra SW, Ataҫ B, Lindner G, Schimek K, Marx U, Gibbs S

2022, Frontiers in Toxicology, A Multi-Organ-on-Chip Approach to Investigate How Oral Exposure to Metals Can Cause Systemic Toxicity Leading to Langerhans Cell Activation in Skin
Koning JJ, Rodrigues Neves CT, Schimek K, Thon M, Spiekstra SW, Waaijman T, de Gruijl TD, Gibbs S

2024, Scientific reports, Vol. 14, Integrating tumor and healthy epithelium in a micro-physiology multi-compartment approach to study renal cell carcinoma pathophysiology
Somova M, Simm S, Padmyastuti A, Ehrhardt J, Schoon J, Wolff I, Burchardt M, Roennau C, Caetano Pinto P

2021, Science, Vol. 373, Human microphysiological systems for drug development
Roth A, MPS-WS Berlin 2019

2021, Frontiers in Medicine, Vol. 8, An Individual Patient's "Body" on Chips – How Organismoid Theory Can Translate Into Your Personal Precision Therapy Approach
Marx U, Accastelli E, David R, Erfurth H, Koenig L, Lauster R, Ramme AP, Reinke P, Volk HD, Winter A, Dehne EM

2014, Advanced Drug Delivery Reviews, Human immunity in vitro - Solving immunogenicity and more
C Giese, U Marx